After years of testing air purifiers for everything from wildfire smoke to pet hair, there’s one question I get all the time: “Should I go with the Medify MA-25 or the MA-40?”
The Medify MA-40 has a stronger airflow (330 CFM compared to 250 CFM) and can handle bigger spaces—up to 1,793 sq ft, while the MA-25 is better suited for smaller areas, covering up to 825 sq ft. The MA-25 is also more compact and runs quieter, with noise levels between 35-51 dB, whereas the MA-40 ranges from 46-66 dB. The MA-40 comes with an optional ionizer to help trap more particles, something the MA-25 doesn’t offer. On the flip side, the MA-25 has a display light dimmer, which the MA-40 lacks. Both use H13 HEPA filters, but the MA-40 has one larger filter that lasts longer (about 3,000 hours) compared to the MA-25’s two smaller ones (around 2,500 hours). Just keep in mind that MA-40 replacement filters tend to cost more.
Both come from a trusted brand known for offering medical-grade filtration without breaking the bank. But even though they look similar at a glance, they’re built for different needs.
In this guide, I’ll break down the key differences based on real-world use, hands-on testing, and specs that actually matter. Whether you’ve got allergies, pets, or just want cleaner air at home, this should help you pick the right one.
Why This Matters
Indoor air quality isn’t just about comfort—it’s about your health. A good purifier can cut down on dust, allergens, smoke, and even viruses. Pick the wrong one, though, and you might end up spending more for features you don’t need—or worse, getting too little protection.
The MA-25 and MA-40 are two of Medify’s most popular models. They both use H13 medical-grade HEPA filters, but they differ a lot in terms of size, power, and use-case. If you’re serious about cleaner air, it’s worth knowing exactly what you’re buying.
MA-25 vs. MA-40: Quick Specs
| Feature | MA-25 | MA-40 |
|---|---|---|
| CADR | 230 CFM | 380 CFM |
| Coverage (4x/hr) | Up to 500 sq ft | Up to 840 sq ft |
| Filter | H13 HEPA + Carbon | H13 HEPA + Carbon |
| Filtration Stages | 3-stage | 3-stage |
| Noise | 35–51 dB | 46–66 dB |
| Fan Speeds | 3 | 4 |
| Ionizer | No | Optional |
| Controls | Touch | Touch |
| Timer/Child Lock | Yes | Yes |
| Filter Indicator | Yes | Yes |
| Power Use | ~28W | ~54W |
| Size (HxWxD) | 13.5″ x 8″ x 8″ | 22″ x 9.9″ x 10.9″ |
| Weight | 7.3 lbs | 15.6 lbs |
| Warranty | Lifetime (with filter subscription) | Lifetime (with filter subscription) |
H13 HEPA: What You’re Actually Getting
Both purifiers use true H13 HEPA filters, which capture 99.9% of particles down to 0.1 microns—better than standard HEPA, which stops at 0.3 microns. That includes:
- Dust
- Pollen
- Mold spores
- Pet dander
- Smoke
- Bacteria and airborne viruses
Each model uses the same basic 3-stage setup:
- Pre-filter for big stuff like hair and dust
- H13 HEPA for the microscopic stuff
- Activated Carbon to absorb odors and VOCs
The MA-40 also has an ionizer option, which helps with odor and particles but isn’t essential for most people. I usually keep it off.
Medify as a Brand
Product Design
Medify focuses on getting hospital-grade air cleaning into homes. Filters are easy to replace, and depending on how often you run them, last about 3–6 months.
Build Quality
From what I’ve seen, both units are solidly made. The MA-40 is heavier and built for constant use. The MA-25 is smaller but still well put together—no cheap plastic or rattling parts.
Customer Support
Support is quick to respond, and the lifetime warranty (if you subscribe to their filters) is one of the best I’ve come across. They’ve sent replacements out fast when there were issues with fans or screens.
Which Works Best Where?
For Bedrooms:
- MA-25 is quiet and compact. Great for sleeping areas.
- MA-40 moves more air, but can be too loud at higher speeds.
For Offices:
- MA-25 fits nicely on a desk or shelf.
- MA-40 is better for larger or shared spaces.
For Allergies:
- MA-40 is the better choice. Higher CADR means it clears out allergens faster.
- MA-25 works for lighter needs or smaller rooms.
For Pet Owners:
- Both help with dander and smell, but the MA-40 handles it better—especially if you turn on the ionizer.
For Open Living Spaces:
- MA-40 is built for this. Can handle large, open rooms.
- MA-25 struggles in areas over 500 sq ft unless you use two.
Pros & Cons
Medify MA-25
Pros:
- Small and light
- Quiet
- Budget-friendly
- Ideal for small rooms
Cons:
- Lower air output
- No ionizer
- Not strong enough for big spaces
Medify MA-40
Pros:
- High CADR
- Covers large areas
- Optional ionizer
- Great for allergies and smoke
Cons:
- Louder
- Takes up more space
- More expensive to run
My Take
After testing both in different conditions—from smoky air to pet-heavy homes—here’s my advice:
If you need something quiet for a small room, go with the MA-25. It’s simple, effective, and easy to live with.
If you’re dealing with allergies, pets, or larger rooms, the MA-40 is worth the extra money. It’s more powerful, and that really makes a difference in how fast and how well it cleans the air.
Personally, I run an MA-40 in my living room and keep an MA-25 in the bedroom. It’s a solid combo.
Final Recommendation
| If You Need… | Choose |
|---|---|
| A quiet bedroom purifier | MA-25 |
| Something affordable | MA-25 |
| To cover 700+ sq ft | MA-40 |
| Help with allergies or pets | MA-40 |
| Fast, powerful air cleaning | MA-40 |
| A compact unit for desk/office use | MA-25 |
Bottom Line
Both the MA-25 and MA-40 deliver top-tier filtration with real H13 HEPA filters. Medify continues to be one of the few brands offering this kind of performance at scale.
Just make sure the one you pick fits your space and your needs. Don’t expect the MA-25 to handle a big living room, and don’t spend on the MA-40 if you just need something small and quiet.
Still not sure? Reach out—I’ve helped a lot of people figure this out.
Breathe better. Live better.
